Up to 40% of postmenopausal women experience vaginal atrophyVaginal atrophy: The thinning, drying, and inflammation of the vaginal walls. This can occur when your body has less estrogen due to menopausal changes. For many women, vaginal atrophy makes intercourse painful., and painful intercourse is a common symptom. Other symptoms of vaginal atrophy may include dryness, burning, and itching in and around the vagina.

With vulvar and vaginal atrophy (VVA)Vaginal atrophy: The thinning, drying, and inflammation of the vaginal walls. This can occur when your body has less estrogen due to menopausal changes. For many women, vaginal atrophy makes intercourse painful., you may experience dryness, burning, and itching in and around the vagina. And having intercourse may be painful. If you’re experiencing painful intercourse, make an appointment to see your doctor and ask them about Premarin Vaginal Cream. To prepare for your appointment, print your Doctor Discussion Guide.

Vaginal symptoms like moderate to severe painful intercourse are unlikely to go away on their own and may even worsen over time. Talk to your doctor about whether Premarin Vaginal Cream may be right for you.

Premarin Vaginal Cream helps rebuild vaginal tissue and make intercourse more comfortable. There is no generic equivalent, so ask your doctor about prescription Premarin Vaginal Cream and see if it may be right for you. Learn more about how Premarin Vaginal Cream can help. 

Talking with your healthcare provider can be your first step in finding relief. Your doctor can properly diagnose your condition. Download our Doctor Discussion Guide to help get the conversation started.

You should apply the cream in accordance with your prescribed dosing regimen. It can be applied at any time of day that's convenient for you.

To treat moderate to severe painful intercourse due to menopause, Premarin Vaginal Cream can be applied twice a week (for example, you might choose Monday and Thursday evening) or in a cyclic regimen of 21 days of therapy, followed by 7 days off therapy, using a 0.5 g dose.

A single tube of prescription Premarin Vaginal Cream can last up to 6 months using the 0.5 g twice weekly dosing regimen.

Estrogens should be used at the lowest effective dose, for the shortest duration consistent with treatment goals and risks for the individual woman. You and your doctor should talk regularly to decide how long you need treatment.

Premarin Vaginal Cream comes with its own applicator to help apply the cream directly. The applicator is designed to help measure your prescribed dosage. Be sure to apply Premarin Vaginal Cream as directed by your doctor. For step-by-step instructions on how to apply Premarin Vaginal Cream, click here.

Your doctor will prescribe the dosage that’s right for you. Estrogens, with or without a progestin, should be used at the lowest effective dose for the shortest duration of time. A single tube of Premarin Vaginal Cream can last up to 6 months depending on the dosing regimen prescribed. To see how to apply and dosing information, click here.

In a clinical study, patients taking Premarin Vaginal Cream had significantly more relief of moderate to severe painful intercourse at 12 weeks than patients taking placebo. Keep in mind, individual results may vary.

There is only one Premarin Vaginal Cream and no generic equivalent is currently available.

Common side effects include headache, pelvic pain, breast pain, vaginal bleeding, and vaginitis. These are not all the possible side effects of Premarin Vaginal Cream. For more information, ask your healthcare provider or pharmacist for advice about side effects. You may report side effects to Pfizer Inc. at 1-800-438-1985 or to FDA at 1-800-FDA-1088. To view other side effects of Premarin Vaginal Cream, click here.

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