Healthcare Professionals

About PREMARIN Vaginal Cream

PREMARIN® (conjugated estrogens) Vaginal Cream targets the underlying cause of painful intercourse at its source.

With regular use, PREMARIN Vaginal Cream is a proven treatment for changes in the vaginal tissue after menopause that can cause painful intercourse.

While using it, PREMARIN Vaginal Cream helps:

  • Restore your vaginal tissue
  • Relieve painful intercourse due to menopause

PREMARIN Vaginal Cream treats painful intercourse after menopause by delivering a blend of estrogens directly to the tissues in and around your vagina — where it’s needed most, so it’s able to treat the underlying cause of painful intercourse right at its source.

When used as prescribed, PREMARIN Vaginal Cream helps you to restore vaginal tissue. That’s something no over-the-counter product was designed to do. With a variety of dosing options, your doctor can tailor your treatment to your needs. And PREMARIN Vaginal Cream uses a non-liquefying base that helps keep it from running.

Apply PREMARIN Vaginal Cream as directed by your health care professional.

Next: Treating the Cause

IMPORTANT SAFETY INFORMATION

Using estrogen-alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using PREMARIN® (conjugated estrogens) Vaginal Cream. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens, with or without progestins, to prevent heart disease, heart attacks, strokes or dementia (decline in brain function). Using estrogens, with or without progestins, may increase your chance of getting dementia, based on a study of women 65 years of age or older.

Using estrogen-alone may increase your chances of getting strokes or blood clots. Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

You and your healthcare provider should talk regularly about whether you still need treatment with PREMARIN® (conjugated estrogens) Vaginal Cream.

PREMARIN® (conjugated estrogens) Vaginal Cream should not be used if you have unusual vaginal bleeding; have or had cancer; had a stroke or heart attack; have or had blood clots or liver problems; have a bleeding disorder; are allergic to any of its ingredients; or think you may be pregnant.

Common side effects include headache, pelvic pain, breast pain, vaginal bleeding and vaginitis.

INDICATION

PREMARIN® (conjugated estrogens) Vaginal Cream is used after menopause to treat menopausal changes in and around the vagina and to treat moderate to severe painful intercourse caused by these changes.

Each gram contains 0.625 mg of conjugated estrogens, USP.

Please see Full Prescribing Information including Boxed Warning and Patient Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

 

Scroll for Important Safety Information and Indication

IMPORTANT SAFETY INFORMATION

Using estrogen-alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using PREMARIN® (conjugated estrogens) Vaginal Cream. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens, with or without progestins, to prevent heart disease, heart attacks, strokes or dementia (decline in brain function). Using estrogens, with or without progestins, may increase your chance of getting dementia, based on a study of women 65 years of age or older.

Using estrogen-alone may increase your chances of getting strokes or blood clots. Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

You and your healthcare provider should talk regularly about whether you still need treatment with PREMARIN® (conjugated estrogens) Vaginal Cream.

PREMARIN® (conjugated estrogens) Vaginal Cream should not be used if you have unusual vaginal bleeding; have or had cancer; had a stroke or heart attack; have or had blood clots or liver problems; have a bleeding disorder; are allergic to any of its ingredients; or think you may be pregnant.

Common side effects include headache, pelvic pain, breast pain, vaginal bleeding and vaginitis.

INDICATION

PREMARIN® (conjugated estrogens) Vaginal Cream is used after menopause to treat menopausal changes in and around the vagina and to treat moderate to severe painful intercourse caused by these changes.

Each gram contains 0.625 mg of conjugated estrogens, USP.

Please see Full Prescribing Information including Boxed Warning and Patient Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.