Home About Premarin Vaginal Cream Treating the Cause

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Premarin Vaginal Cream treats the cause,
not just the symptoms.

If you're experiencing vaginal dryness or painful intercourse after menopause, you might try over-the-counter lubricants first. They may give you some temporary relief from your symptoms. But the fact is, they weren't designed to do what a prescription treatment can.

Premarin Vaginal Cream is a topical estrogen treatment that targets the underlying cause of painful intercourse at its source. While you use it, it actually restores the vaginal tissue that provides lubrication naturally so sex can be more comfortable.

You can apply Premarin Vaginal Cream any time of the day that's convenient for you, and you don't need to use it forever. You and your doctor should talk regularly to decide how long you need treatment.

Important Safety Information
What is the most important information I should know about PREMARIN Vaginal Cream (an estrogen mixture)?

  • Using estrogen-alone may increase your chance of getting cancer of the uterus (womb)
  • Report any unusual vaginal bleeding right away while you are using PREMARIN Vaginal Cream. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find the cause
  • Do not use estrogen-alone to prevent heart disease, heart attacks, strokes or dementia (decline in brain function)
  • Using estrogen-alone may increase your chances of getting strokes or blood clots
  • Do not use estrogens with progestins to prevent heart disease, heart attacks, or dementia
  • Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots
  • Using estrogens with progestins may increase your chance of getting dementia, based on a study of women age 65 years or older
  • You and your healthcare provider should talk regularly about whether you still need treatment with PREMARIN Vaginal Cream

PREMARIN® Vaginal Cream is used after menopause to treat menopausal changes in and around the vagina and painful intercourse caused by these changes.

It should not be used if you have unusual vaginal bleeding, have or had cancer of the breast or uterus, had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of its ingredients, or think you may be pregnant.

Most common side effects include headache, infection, abdominal pain, back pain, accidental injury, and vaginitis.

Please see Patient Information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call
1-800-FDA-1088.

Ask your doctor if Premarin Vaginal Cream is right for you

Symptoms
and Causes

While some symptoms of menopause may lessen over time, painful intercourse can persist and become more bothersome without treatment. Find out more about the symptoms and causes of vaginal atrophy

How your doctor
can help

Premarin Vaginal Cream is an effective treatment for painful intercourse due to menopause that might be right for you. Discover simple ways to get the conversation started with your
doctor