How much cream will you need?
Premarin Vaginal Cream is a topical estrogen treatment with a low-dose option, so your doctor can tailor your dosage to your individual needs. That means, for treating painful sex due to menopause, you can use as little as just a half gram applied twice a week. That's roughly the same size as a cranberry. And, its formulation is designed to not liquify, so it's not messy. Use Premarin Vaginal Cream as directed by your doctor.
When do you apply the cream?
You can apply Premarin Vaginal Cream any time of the day that's convenient for you. Used just two times a week, (for example Monday and Thursday), it can help relieve painful intercourse due to menopause and you don't need to use it forever. You and your doctor should talk regularly to decide how long you need treatment. Apply Premarin Vaginal Cream as directed by your doctor.
Where is it applied?
Premarin Vaginal Cream can be applied directly to vaginal tissues for targeted relief of your symptoms. And its formulation is designed to not liquify, so it's not messy.
How is it applied?
Premarin Vaginal Cream comes with its own applicator that helps you apply it directly to your vaginal tissue. The applicator is designed to help you measure your prescribed dosage neatly and precisely, for comfortable, easy use.
To see step-by-step instructions, click here.
How long does it take to work?
In clinical studies, women using Premarin Vaginal Cream experienced relief from vaginal discomfort and painful intercourse due to menopause within 3-4 weeks.
Important Safety Information
What is the most important information I should know about PREMARIN Vaginal Cream (an estrogen mixture)?
- Using estrogen-alone may increase your chance of getting cancer of the uterus (womb)
- Report any unusual vaginal bleeding right away while you are using PREMARIN Vaginal Cream. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find the cause
- Do not use estrogen-alone to prevent heart disease, heart attacks, strokes or dementia (decline in brain function)
- Using estrogen-alone may increase your chances of getting strokes or blood clots
- Do not use estrogens with progestins to prevent heart disease, heart attacks, or dementia
- Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots
- Using estrogens with progestins may increase your chance of getting dementia, based on a study of women age 65 years or older
- You and your healthcare provider should talk regularly about whether you still need treatment with PREMARIN Vaginal Cream
PREMARIN® Vaginal Cream is used after menopause to treat menopausal changes in and around the vagina and painful intercourse caused by these changes.
It should not be used if you have unusual vaginal bleeding, have or had cancer of the breast or uterus, had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of its ingredients, or think you may be pregnant.
Most common side effects include headache, infection, abdominal pain, back pain, accidental injury, and vaginitis.
Please see Patient Information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call
1-800-FDA-1088.