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A painful side of menopause.

You may have expected the hot flashes and night sweats of menopause. But vaginal dryness and painful intercourse may have come as a surprise.

For many women, intercourse becomes painful after menopause because of changes in the vaginal tissue. During menopause, low levels of the female hormone estrogen cause natural lubrication to diminish and vaginal walls to become dry and thin. This common medical condition is called vaginal atrophy.

While some symptoms of menopause may lessen over time, painful intercourse can continue and become more bothersome without treatment.

The good news is that vaginal atrophy and painful intercourse due to menopause can be effectively treated to provide relief.

If you are experiencing painful intercourse after menopause, knowing more about vaginal atrophy, and what causes it, can help you understand the importance of finding a treatment that addresses the underlying problem. Premarin Vaginal Cream is a prescription treatment proven to restore the vaginal tissue that provides lubrication after menopause. While you use it, it helps your body create its own inner moisture to help relieve painful intercourse due to menopause. That's something no over-the-counter product was designed to do.

Important Safety Information
What is the most important information I should know about PREMARIN Vaginal Cream (an estrogen mixture)?

  • Using estrogen-alone may increase your chance of getting cancer of the uterus (womb)
  • Report any unusual vaginal bleeding right away while you are using PREMARIN Vaginal Cream. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find the cause
  • Do not use estrogen-alone to prevent heart disease, heart attacks, strokes or dementia (decline in brain function)
  • Using estrogen-alone may increase your chances of getting strokes or blood clots
  • Do not use estrogens with progestins to prevent heart disease, heart attacks, or dementia
  • Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots
  • Using estrogens with progestins may increase your chance of getting dementia, based on a study of women age 65 years or older
  • You and your healthcare provider should talk regularly about whether you still need treatment with PREMARIN Vaginal Cream

PREMARIN® Vaginal Cream is used after menopause to treat menopausal changes in and around the vagina and painful intercourse caused by these changes.

It should not be used if you have unusual vaginal bleeding, have or had cancer of the breast or uterus, had a stroke or heart attack, have or had blood clots or liver problems, are allergic to any of its ingredients, or think you may be pregnant.

Most common side effects include headache, infection, abdominal pain, back pain, accidental injury, and vaginitis.

Please see Patient Information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call
1-800-FDA-1088.

Ask your doctor if Premarin Vaginal Cream is right for you

How your doctor
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Premarin Vaginal Cream is an effective treatment for painful intercourse due to menopause that might be right for you. Discover simple ways to get the conversation started with your
doctor

Find out more
about Premarin
Vaginal Cream

Discover how Premarin Vaginal Cream can actually restore your body's natural ability to lubricate while you use it. Learn more about Premarin Vaginal
Cream